FINAL PROGRAM
Sunday April 8 – Wednesday April 11, 2018

Sunday Evening Session (Marriott Hotel Medical Center):
  • FAMILY Q&A SESSIONS: English (Shimamura, USA, Sasa, USA, Leung, USA) and Spanish (Bacino, USA, Diaz, USA, Martinez, USA) 4:00-4:30
  • LECTURE: Review of current diagnostic criteria using the previous two international consensus reports; and introduction to the congress agenda (Shimamura/Bertuch, USA) 4:30-5:30
  • OPENING RECEPTION: 5:30-7:00
Monday Morning Session (Rice University, BRC Building):
SDS DEFINITION AND GENETICS

(Chairs Rommens, Canada, Bacino, USA)

  • Welcome and opening remarks: 8:15-8:30 (Local Committee)
  • SDS as a ribosomal disorder (Baserga, USA): 8:30-9:00
  • SDS current issues with definition (Donadieu, France): 9:00-9:30
  • EFL1 deficiency causes Shwachman-Diamond syndrome in humans and mice (Revy, France): 9:30-10:00
    • Coffee Break 10:00-10:30
  • Experience with SDS and SDS-like genetics (Dror, Canada): 10:30-11:00
  • Selected abstracts: 11:00-12:00
  • SDS genetics and definition roundtable (Rommens, Canada, Dror, Canada, Zeidler, Germany): 12:00-12:45
    • Lunch and Poster View (odd number posters): 12:45-2:00
Monday Afternoon Session (Rice University, BRC Building):
BASIC SCIENCE, HEMATOPOIESIS AND STEM CELLS

(Chairs Vulliamy, UK, Bertuch, USA)

  • Ribosome assembly, new findings (Warren’s group, UK) 2:00-2:30
  • Characterization of DNAJC21 as a bone marrow failure gene (Vulliamy, UK) 2:30-3:00
  • Hematopoiesis in SDS (Myers, USA) 3:00-3:30
    • Coffee break 3:30-4:00
  • Hematopoietic stem cell defects in SDS (Raaijmakers, The Netherlands) 4:00-4:30
  • Selected abstracts 4:30-6:00
Tuesday Morning Session (Rice University, BRC Building):
CLINICAL ASPECTS I: HEMATOLOGIC MANIFESTATIONS AND CLONAL EVOLUTION

(Chairs Shimamura, USA, Elghetany USA)

  • Hematologic complications of SDS (Alter, USA): 8:30-9:00
  • Management of hematologic issues in adults and in adolescents transitioning into adulthood (Liu, USA) 9:00-9:30
  • Novel recurrent chromosomal changes and gene expression related to chromosome anomalies (Valli, Italy): 9:30-10:00
    • Coffee break 10:00-10:30
  • Clonal evolution in SDS (Delhommeau, France) 10:30-11:00
  • Clonal evolution in SDS (Delhommeau, France) 10:45-11:15
  • Selected abstracts 11:00-11:45
    • Lunch and Poster View (even number posters) 11:45-1:00
Tuesday Afternoon Session (Rice University, BRC Building):
LECTURE (introduction by Davies, USA) Prognostic mutations after stem cell transplantation (Lindsley, USA) 1:00-1:45
CLINICAL ASPECTS II

(Chairs Sasa, USA, Alter, USA)

  • SDS nutritional status and management (Ooi, Australia) 1:45-2:15
  • Liver issues in SDS (Leung, USA) 2:15-2:35
    • Coffee break 2:35-3:00
  • Management of pregnancy in SDS (Giri, USA) 3:00-3:20
  • Novel myopathy revealed in a newborn with severe hypotonia and thoracic dysplasia (Topa, Sweden) 3:20-3:40
  • Neuropsychiatric evaluation (Kerr, Canada) 3:40-4:00
  • Selected abstracts: 4:00-4:45
Tuesday Evening: (tentatively at SPACE CENTER - NASA)
GALA DINNER Dinner 6:00-10:00 (separate registration required)
Wednesday Morning Session (Rice University, BRC Building):
TRANSPLANT AND NOVEL THERAPIES

(Chairs Myers, USA, Donadiue, France)

  • Review of SDS BMT experience (Davies, USA) 8:30-9:00
  • Novel therapies (Cipolli, Italy) 9:00-9:20
  • Novel therapies (Warren, UK) 9:20-9:40
  • Novel therapies with 7q- MDS (Shimamura, USA): 9:40-10:00
    • Coffee Break 10:00-10:20
  • Selected abstracts 10:20-11:00
CONFERENCE SUMMARY, FUTURE DIRECTION, DATA SHARING, AND ANNOUNCEMENTS

(Shimamura, USA, Cipolli, Italy, Rommens, Canada, Zeidler, Germany) 11:00-11:50

CONFERENCE CONCLUDES NOON WEDNESDAY

Organizing secretariat
Città Affari sas – Mrs Flavia Pizzini
Lungadige G. Matteotti, 2
37126 Verona
Tel. +39 045 917806 Mob. +39 348 3341695
Web: www.sdscongresshouston.com
Email: info@sdscongresshouston.com

Local Organizing Committee Chairs
Dr. Tarek Elghetany
Dr. Alison Bertuch